Arizona Cardinals vs San Francisco 49ers : NFL's Thursday Night Football Week 5 Football Game - Who Will Win?

It's Thursday Night Football on Thursday October 06, 2016 at 5:30 PM PDT at Levi's Stadium for the NFL's week 5 game of TNF match between Arizona Cardinals vs San Francisco 49ers they battle it up especially it's the opening season for NFL were in Trevor Siemian is set to follow in footsteps of the very accurate Peyton Manning while for Cam Newton it's just the season opener, not a title game. That is enough for Newton, the Carolina Panthers‘ quarterback, to downplay the whole thing and maybe the most intriguing spotlight is the one on Newton, who with an MVP trophy on his shelf, a Super Bowl trip in his rearview mirror and a 27th birthday recently in the books, is perhaps primed for a transition. This is Newton’s league in which at 6-foot-5, 245 pounds and in full command of accuracy and throwing skills there is little he isn’t capable of. He was the overwhelming reason Carolina carried a 17-1 record into that Super Bowl, including a lopsided NFC championship game victory. The Panther offense came in averaging 31.3 points a game as 45 of the team’s 54 offensive touchdowns came courtesy of Newton’s arm (35) or legs (10) and yet Denver stuffed and stifled him. Newton went 18-of-41 in the Super Bowl, with no touchdowns, one pick and two lost fumbles as the last season was a charmed one for Newton and the Panthers. They started 14-0. Playoffs included there were nine double-digit victories. Cam found the perfect balance of throwing and passing. Everything came together, until it didn’t. See all the excitement in today's NFL week 1 opening game.